tui ole Enrofloxacin

Pharmacodynamic Enrofloxacin o se vailaʻau faʻamaʻi faʻamaʻi lautele faʻapitoa e faʻaaogaina mo manu fluoroquinolone.Mo e.coli, salmonella, klebsiella, brucella, pasteurella, pleuropneumonia actinobacillus, erysipelas, bacillus proteus, palapala omea Mr Charest's bacteria, suppurative corynebacterium, faʻatoʻilaloina siama toto toto, staphylococcus aureus, mycoplasma, chlamydia, ma isi mea uma o loʻo i ai le aafiaga lelei o le chlamydia, ma isi mea uma. ma streptococcus e vaivai, vaivai aafiaga i siama anaerobic.E manino le a'afiaga pe a uma le antibacterial i siama ma'ale'ale.O le gaioiga faʻamaʻi a le antibacterial o lenei oloa o le faʻalavelaveina o le DNA siama, faʻalavelave i le toe faia, faʻaliliu ma toe faʻaleleia o le DNA faʻamaʻi pipisi, e le mafai ona tupu aʻe siama ma toe faʻaleleia masani ma mate.

Pharmacokinetics O le vailaʻau na faʻafefe vave ma atoatoa e ala ile tui intramuscular.O le bioavailability o 91.9% i puaa ma 82% i povi.E salalau lautele i manu ma e mafai ona ulu lelei i totonu o le tino ma sua o le tino.Vagana ai le sua o le cerebrospinal, o le faʻaogaina o vailaʻau i le toetoe o masini uma e maualuga atu nai lo le plasma.O le metabolism autu o le ate o le aveesea lea o le ethyl o le mama 7-piperazine e maua ai le ciprofloxacin, sosoo ai ma le oxidation ma le glucuronic acid binding.E masani lava e ala ile fatuga'o (fa'alilo tubular renal ma filtration glomerular) lafoaia, 15% ~ 50% i le uluai foliga mai le mimi.O le faʻaumatiaina o le afa-ola o tui intramuscular e 5.9 itula i povi susu, 1.5 ~ 4.5 itula i mamoe, ma 4.6 itula i puaa.